A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10077
Swiss-prot Accession numberQ92097 (Sequence in FASTA format)
DescriptionProgonadoliberin-3 precursor (Progonadoliberin III) [Contains:Gonadoliberin-3 (Gonadoliberin III) (Luteinizing hormone-releasinghormone III) (LH-RH III) (Gonadotropin-releasing hormone III) (GnRHIII) (Luliberin III); GnRH-associated peptide 3 (GnRH-associatedpeptide III)] (Fragment).
Source organismOncorhynchus tschawytscha (Chinook salmon) (King salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the GnRH family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionStimulates the secretion of gonadotropins
Protein Length74 Amino acids
Molecular weight8254
References1  PubMed abstract 1587389
Domain NameN/A
Hormone NameGonadoliberin-3
Mature Hormone SequenceQHWSYGWLPG
Position of mature hormone in Pre-Hormone protein10 Residues from position (16-25)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10224
Swiss-prot Accession numberQ91364 (Sequence in FASTA format)
DescriptionProlactin-2 precursor (Prolactin II) (PRL-II).
Source organismOncorhynchus tschawytscha (Chinook salmon) (King salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length210 Amino acids
Molecular weight23457
References1  PubMed abstract 1308811
Domain NameHormone_1  
Hormone NameProlactin-2
Mature Hormone SequenceIGLSDLMERASQRSDKLHSLSTSLNKDLDSHFPPMGRVMMPRPSMCHTSSLQIPKDKEQALRVSENELISLARSLLLAWNDPLLLLSSEAPTLPHPSNGDISSKIRELQDYSKSLGDGLDILVNKMGPSSQYISLIPFKGGDLGNDKTSRLINFHFLMSCFRRDSHKIDSFLKVLRCRATKMRPETC
Position of mature hormone in Pre-Hormone protein187 Residues from position (24-210)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10443
Swiss-prot Accession numberP17640 (Sequence in FASTA format)
DescriptionPro-MCH 1 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)].
Source organismOncorhynchus tschawytscha (Chinook salmon) (King salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the melanin-concentrating hormone family.
Tissue SpecificityPituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released
Post translational modificationN/A
FunctionPlays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH
Protein Length132 Amino acids
Molecular weight14657
References1  PubMed abstract 2471200
Domain NameN/A
Hormone NameMelanin-concentrating hormone
Mature Hormone SequenceDTMRCMVGRVYRPCWEV
Position of mature hormone in Pre-Hormone protein17 Residues from position (116-132)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10501
Swiss-prot Accession numberP69156 (Sequence in FASTA format)
DescriptionPro-MCH 2 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)].
Source organismOncorhynchus tschawytscha (Chinook salmon) (King salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the melanin-concentrating hormone family.
Tissue SpecificityPituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released
Post translational modificationN/A
FunctionN/A
Protein Length132 Amino acids
Molecular weight14710
References1  PubMed abstract 2471200
Domain NameN/A
Hormone NameNeuropeptide-glutamic acid-valine
Mature Hormone SequenceEADQDLSPSISIV
Position of mature hormone in Pre-Hormone protein13 Residues from position (101-113)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10502
Swiss-prot Accession numberP69156 (Sequence in FASTA format)
DescriptionPro-MCH 2 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)].
Source organismOncorhynchus tschawytscha (Chinook salmon) (King salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the melanin-concentrating hormone family.
Tissue SpecificityPituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released
Post translational modificationN/A
Function Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH
Protein Length132 Amino acids
Molecular weight14710
References1  PubMed abstract 2471200
Domain NameN/A
Hormone NameMelanin-concentrating hormone
Mature Hormone SequenceDTMRCMVGRVYRPCWEV
Position of mature hormone in Pre-Hormone protein17 Residues from position (116-132)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10618
Swiss-prot Accession numberP69062 (Sequence in FASTA format)
DescriptionGlycoprotein hormones alpha chain 2 precursor (Gonadotropin 2 alphachain) (GTH-alpha).
Source organismOncorhynchus tschawytscha (Chinook salmon) (King salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit alpha family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInvolved in gametogenesis and steroidogenesis
Protein Length114 Amino acids
Molecular weight12538
References1  PubMed abstract 7749461
Domain NameHormone_6  
Hormone NameGlycoprotein hormones alpha chain 2
Mature Hormone SequenceYPNSDKTNMGCEECTLKPNTIFPNIMQCTGCCFSRAYPTPLRSKQTMLVPKNITSEATCCVAKEGERVTTKDGFPVTNHTECHCSTCYYHKS
Position of mature hormone in Pre-Hormone protein92 Residues from position (23-114)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10752
Swiss-prot Accession numberQ07221 (Sequence in FASTA format)
DescriptionSomatotropin precursor (Growth hormone).
Source organismOncorhynchus tschawytscha (Chinook salmon) (King salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation
Protein Length210 Amino acids
Molecular weight23892
References1  PubMed abstract 1466911
2   Song S., Trinh K.T., Hew C.-L.; Yi Chuan Xue Bao 20:380-380(1993).
Domain NameHormone_1  
Hormone NameSomatotropin
Mature Hormone SequenceIENQRLFNIAVSRVQHLHLLAQKMFNDFDGTLLPDERRQLNKIFLLDFCNSDSIVSPVDKHETQKSSVLKLLHISFRLIESWEYPSQTLIISNSLMVRNANQISEKLSDLKVGINLLITGSQDAYMSLDDNDSQQLPPYGNYYQNLGGDGNVRRNYELLACFKKDMHKVETYLTVAKCRKSLEANCTL
Position of mature hormone in Pre-Hormone protein188 Residues from position (23-210)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number11000
Swiss-prot Accession numberP69131 (Sequence in FASTA format)
DescriptionProlactin-1 precursor (Prolactin I) (PRL-I).
Source organismOncorhynchus tschawytscha (Chinook salmon) (King salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length211 Amino acids
Molecular weight23559
References1  PubMed abstract 3349998
Domain NameHormone_1  
Hormone NameProlactin-1
Mature Hormone SequenceIGLSDLMERASQRSDKLHSLSTSLTKDLDSHFPPMGRVMMPRPSMCHTSSLQTPKDKEQALKVSENELISLARYLLLAWNDPLLLLSSEAPTLPHTPSNGDISSKIRELQDYSKSLGDGLDIMVNKMGPSSQYISSIPFKGGDLGNDKTSRLINFHFLMSCFRRDSHKIDSFLKVLRCRATNMRPETC
Position of mature hormone in Pre-Hormone protein188 Residues from position (24-211)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated