A database of hormones and their receptors |
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HMRbase accession number | 10077 |
Swiss-prot Accession number | Q92097 (Sequence in FASTA format) |
Description | Progonadoliberin-3 precursor (Progonadoliberin III) [Contains:Gonadoliberin-3 (Gonadoliberin III) (Luteinizing hormone-releasinghormone III) (LH-RH III) (Gonadotropin-releasing hormone III) (GnRHIII) (Luliberin III); GnRH-associated peptide 3 (GnRH-associatedpeptide III)] (Fragment). |
Source organism | Oncorhynchus tschawytscha (Chinook salmon) (King salmon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 74 Amino acids |
Molecular weight | 8254 |
References | 1 PubMed abstract 1587389 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-3 |
Mature Hormone Sequence | QHWSYGWLPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (16-25) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10224 |
Swiss-prot Accession number | Q91364 (Sequence in FASTA format) |
Description | Prolactin-2 precursor (Prolactin II) (PRL-II). |
Source organism | Oncorhynchus tschawytscha (Chinook salmon) (King salmon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the somatotropin/prolactin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 210 Amino acids |
Molecular weight | 23457 |
References | 1 PubMed abstract 1308811 |
Domain Name | Hormone_1 |
Hormone Name | Prolactin-2 |
Mature Hormone Sequence | IGLSDLMERASQRSDKLHSLSTSLNKDLDSHFPPMGRVMMPRPSMCHTSSLQIPKDKEQALRVSENELISLARSLLLAWNDPLLLLSSEAPTLPHPSNGDISSKIRELQDYSKSLGDGLDILVNKMGPSSQYISLIPFKGGDLGNDKTSRLINFHFLMSCFRRDSHKIDSFLKVLRCRATKMRPETC |
Position of mature hormone in Pre-Hormone protein | 187 Residues from position (24-210) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10443 |
Swiss-prot Accession number | P17640 (Sequence in FASTA format) |
Description | Pro-MCH 1 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)]. |
Source organism | Oncorhynchus tschawytscha (Chinook salmon) (King salmon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the melanin-concentrating hormone family. |
Tissue Specificity | Pituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released |
Post translational modification | N/A |
Function | Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH |
Protein Length | 132 Amino acids |
Molecular weight | 14657 |
References | 1 PubMed abstract 2471200 |
Domain Name | N/A |
Hormone Name | Melanin-concentrating hormone |
Mature Hormone Sequence | DTMRCMVGRVYRPCWEV |
Position of mature hormone in Pre-Hormone protein | 17 Residues from position (116-132) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10501 |
Swiss-prot Accession number | P69156 (Sequence in FASTA format) |
Description | Pro-MCH 2 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)]. |
Source organism | Oncorhynchus tschawytscha (Chinook salmon) (King salmon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the melanin-concentrating hormone family. |
Tissue Specificity | Pituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released |
Post translational modification | N/A |
Function | N/A |
Protein Length | 132 Amino acids |
Molecular weight | 14710 |
References | 1 PubMed abstract 2471200 |
Domain Name | N/A |
Hormone Name | Neuropeptide-glutamic acid-valine |
Mature Hormone Sequence | EADQDLSPSISIV |
Position of mature hormone in Pre-Hormone protein | 13 Residues from position (101-113) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10502 |
Swiss-prot Accession number | P69156 (Sequence in FASTA format) |
Description | Pro-MCH 2 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)]. |
Source organism | Oncorhynchus tschawytscha (Chinook salmon) (King salmon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the melanin-concentrating hormone family. |
Tissue Specificity | Pituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released |
Post translational modification | N/A |
Function | Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH |
Protein Length | 132 Amino acids |
Molecular weight | 14710 |
References | 1 PubMed abstract 2471200 |
Domain Name | N/A |
Hormone Name | Melanin-concentrating hormone |
Mature Hormone Sequence | DTMRCMVGRVYRPCWEV |
Position of mature hormone in Pre-Hormone protein | 17 Residues from position (116-132) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10618 |
Swiss-prot Accession number | P69062 (Sequence in FASTA format) |
Description | Glycoprotein hormones alpha chain 2 precursor (Gonadotropin 2 alphachain) (GTH-alpha). |
Source organism | Oncorhynchus tschawytscha (Chinook salmon) (King salmon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the glycoprotein hormones subunit alpha family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Involved in gametogenesis and steroidogenesis |
Protein Length | 114 Amino acids |
Molecular weight | 12538 |
References | 1 PubMed abstract 7749461 |
Domain Name | Hormone_6 |
Hormone Name | Glycoprotein hormones alpha chain 2 |
Mature Hormone Sequence | YPNSDKTNMGCEECTLKPNTIFPNIMQCTGCCFSRAYPTPLRSKQTMLVPKNITSEATCCVAKEGERVTTKDGFPVTNHTECHCSTCYYHKS |
Position of mature hormone in Pre-Hormone protein | 92 Residues from position (23-114) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10752 |
Swiss-prot Accession number | Q07221 (Sequence in FASTA format) |
Description | Somatotropin precursor (Growth hormone). |
Source organism | Oncorhynchus tschawytscha (Chinook salmon) (King salmon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the somatotropin/prolactin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation |
Protein Length | 210 Amino acids |
Molecular weight | 23892 |
References | 1 PubMed abstract 1466911 2 Song S., Trinh K.T., Hew C.-L.; Yi Chuan Xue Bao 20:380-380(1993). |
Domain Name | Hormone_1 |
Hormone Name | Somatotropin |
Mature Hormone Sequence | IENQRLFNIAVSRVQHLHLLAQKMFNDFDGTLLPDERRQLNKIFLLDFCNSDSIVSPVDKHETQKSSVLKLLHISFRLIESWEYPSQTLIISNSLMVRNANQISEKLSDLKVGINLLITGSQDAYMSLDDNDSQQLPPYGNYYQNLGGDGNVRRNYELLACFKKDMHKVETYLTVAKCRKSLEANCTL |
Position of mature hormone in Pre-Hormone protein | 188 Residues from position (23-210) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11000 |
Swiss-prot Accession number | P69131 (Sequence in FASTA format) |
Description | Prolactin-1 precursor (Prolactin I) (PRL-I). |
Source organism | Oncorhynchus tschawytscha (Chinook salmon) (King salmon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the somatotropin/prolactin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 211 Amino acids |
Molecular weight | 23559 |
References | 1 PubMed abstract 3349998 |
Domain Name | Hormone_1 |
Hormone Name | Prolactin-1 |
Mature Hormone Sequence | IGLSDLMERASQRSDKLHSLSTSLTKDLDSHFPPMGRVMMPRPSMCHTSSLQTPKDKEQALKVSENELISLARYLLLAWNDPLLLLSSEAPTLPHTPSNGDISSKIRELQDYSKSLGDGLDIMVNKMGPSSQYISSIPFKGGDLGNDKTSRLINFHFLMSCFRRDSHKIDSFLKVLRCRATNMRPETC |
Position of mature hormone in Pre-Hormone protein | 188 Residues from position (24-211) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |